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Synthesis of Lycopene

Apr 06, 2017

Lycopene is not only distributed in tomatoes, but also in the wood turtle fruit, watermelon, pumpkin, plum, persimmon, pepper fruit, peach, papaya, mango, guava, grape, grapefruit, cranberry, Fruit, tea leaves and radish, carrot, turnip cabbage and other roots. Tomato and its products lycopene is the most important source of carotenoids in Western diets, the human lycopene obtained from tomatoes accounted for more than 80% of the total intake.

 In addition to plants such as lycopene and other carotenoids, some microorganisms, such as red fecal yeast, algae, into the group of some of the kinds of bacteria can produce carotenoids, especially red hair foliage and green algae, Of the relatively high yield of astaxanthin, yeast and E. coli genetic transformation also makes itself does not produce carotenoid micro-organisms can be the synthesis of such substances. Lycopene biosynthetic pathway:

Lycopene is a kind of carotenoids, the human body can not synthesize carotenoids, must be through the outside intake; but carotenoids in many plants in low content, and difficult to use chemical synthesis, mainly through biosynthesis Way to finish. Biosynthetic pathway carotenoid biosynthesis can be synthesized by acetyl-CoA via hydroxymethylglutaryl-CoA pathway on fungal and plant cell cytoplasmic / endoplasmic reticulum via different routes. In the bacteria and plant plastid by glyceraldehyde and pyruvate by 1-deoxymethanone-5-phosphate pathway synthesis of the formation of isopentenyl pyrophosphoric acid by repeated condensation to generate the first carotene octahydro Tomato And then converted to other carotenoids by dehydrogenation, cyclization, hydroxylation, epoxidation and the like.