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Biological characteristics of lycopene

Apr 06, 2017

Lycopene by physical and chemical quenching of singlet oxygen or capture of free radicals. Single-phase oxygen is a highly active oxygen free radicals, with cytotoxic effects, the cell membrane, mitochondria and other parts of its most sensitive to the cells with a variety of biological macromolecules, through the combination of molecules caused by cell membrane damage ; Lycopene can accept the energy of different electron excited states, absorb light energy and through the singlet-singlet state energy transfer process so that single-phase oxygen energy transfer to lycopene, generate ground state oxygen molecules and triplet lycopene molecules, The triplet lycopene is regenerated by a series of optical and vibratory reactions with the solvent and distributes energy during this process; the carotenoid quenching ability is closely related to the number of conjugated double bonds contained in its molecule , Lycopene molecules have 11 conjugated double bonds, a lycopene molecule can remove thousands of singlet oxygen, the quenching of singlet oxygen rate constant than β-carotene 2 times higher. 1990 Paolo and other reports of carotenoids and tocopherol and other more than 30 kinds of biological antioxidants quenching the role of singlet oxygen, lycopene is quenching singlet oxygen the strongest.

Lycopene also oxidizes free radicals by oxidizing free radicals with oxidative free radicals such as hydrogen peroxide and nitrite, and oxidizing free radicals to cause lipid peroxidation to form a variety of products by chemical reactions with other forms of reactive oxygen species. And human aging, cancer, autoimmune diseases and anemia and other diseases are related.